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. 2020 Oct 11;25(20):4625. doi: 10.3390/molecules25204625

Table 5.

Pharmacokinetic parameters of metformin in human plasma after administration of a single 1000 mg dose of metformin.

Parameter Value
Mean SD
Cmax (ng/mL) 3187.6 1316.2
Tmax (h) 1.97 [1.00, 3.02] a
AUClast (ng·h/mL) 18474.6 8589.5

The peak plasma concentration (Cmax), the area under the plasma concentration-time curve from time zero to the time of the last measurable concentration (AUClast), and the time to reach the Cmax (Tmax); a median [min, max].