Table 2.
Concentrations of serum inflammatory cytokines from mice treated intraperitoneally with 8, 250, 500 and 1000 mg/kg extract of the Sechium H387 07 hybrid.
| Cytokine (pg/mL) | Without Treatment |
H387 07 Hybrid Extract (mg/kg) | ||||
|---|---|---|---|---|---|---|
| 0 | 8 | 250 | 500 | 1000 | ||
| TNFα | 255.7 ± 37 | 257.9 ± 26 | 144.8 ± 42 * | 200.4 ± 9 * | 143.1 ± 23 * | 92.46 ± 25 * |
| INFγ | 69.7 ± 6 | 56.6 ± 3 | 49.6 ± 7 | 27.5 ± 8 * | 19.07 ± 6 * | 26.9 ± 3 * |
| IL-6 | 590.0 ± 56 | 512.5 ± 60 | 125.8 ± 47 * | 378.7 ± 20 * | 231 ± 41 * | 237 ± 27 * |
| IL-10 | 342.6 ± 75 | 276.9 ± 82 | 1070 ± 375 * | 2831 ± 168 * | 3870 ± 480 * | 4156 ± 200 * |
n = 10 mice per treatment ± standard deviation, * ANOVA, significant difference (Tukey p < 0.05).