Table 3. Metabolic Inhibitor-Induced Changes in Redox Ratios of Quiescent and Activated T cells a .
Definition Method | ||||||||
---|---|---|---|---|---|---|---|---|
Activation Status | A | Q | A | Q | A | Q | A | Q |
Rotenone + Antimycin A | — | ↓ | — | ↑ | — | ↓ | ↓ | ↓ |
2DG | ↑ | ↓ | ↓ | ↑ | ↑ | ↓ | ↓ | — |
TOFA | — | ↓ | — | ↑ | — | ↓ | ↓ | ↓ |
BPTES | ↑ | — | ↓ | ↑ | ↑ | ↓ | ↓ | ↓ |
2DG: 2-deoxy-d-glucose, TOFA: 5-(Tetradecyloxy)-2-furoic acid, BPTES: Bis-2-(5-phenylacetamido-1,3,4-thiadiazol-2-yl) ethyl sulfide; A: Activated; Q: Quiescent. FLIRR trends inconsistent with intensity-based redox ratios denoted with shading.