Figure 4.
(a): Inhibition of the biosynthesis of 5-LO products in stimulated HEK293 cells by zileuton (1; 1 μM), SAPE (2; 1 μM), and 11–21 (1 μM). Data are expressed as means ± SEM of at least three independent experiments. Values without one common superscript are significantly different determined by one-way ANOVA with Tukey’s multiple comparison test (p < 0.05). (b): Inhibition of the biosynthesis of 5-LO products in stimulated HEK293 cells by zileuton (1; 1 μM), SAPE (2; 1 μM), and 22–31 (1 μM). Data are expressed as means ± SEM of at least three independent experiments. Values without one common superscript (a, b, c, d, or e) are significantly different determined by one-way ANOVA with Tukey’s multiple comparison test (p < 0.05).