FIGURE 3.

Schematic summary of major functional studies in the last 32 years suggesting the identification of specific NP opsonins and dysopsonins. The indicated studies (detailed in the text) and their publication years are compared with major general achievements (arrows) in the fields. Dysopsonins are in red, while opsonins are in green. In the case of C3b opsonin, the complement triggers are indicated in white within brackets. Studies performed using phagocytes are on top, while studies performed using epithelial or endothelial cells are on the bottom.