Table 4.
Effects of liquid lipid level on the properties of NLCs.
| Lipid(s) | Change of Liquid Lipid Level | Results | Reference |
|---|---|---|---|
| Tristearin, soya lecithin | 20–50% * | Decrease in PS (426–311 nm) and PDI (0.38–0.24) | [160] |
| Tripalmitin, Phosal® 53MCT | 0–50% * | From 0–40%: decreases in PS (479–185 nm) and PDI (0.441–0.214), increases in EE (81.2–93.2%) and DL (9.21–10.43%) From 40–50%: significant increases in PS (to 213 nm) and PDI (to 0.521) |
[76] |
| Glycerin monostearate, oleic acid | 15–30 mg | Decrease in PS (210–194 nm) and PDI (0.355–0.242), increase in EE (83.9–93.3%) | [42] |
| Tristearin, distearoyl-phosphatidyl ethanolamine | 33–67% * | From 33–50%: slight increase in PS (186–195 nm), decrease in PDI (0.388–0.265) From 50–67%: increase in PS (19–233 nm) and PDI (0.265–0.404) |
[155] |
| Stearic acid, hosphatidylcholine | 5–15 mg/mL | From 5–10 mg/mL: decreases in PS (283–234 nm) and PDI (0.57–0.41) From 10–15 mg/mL: increases in PS (234–247 nm) and PDI (0.41–0.68) |
[169] |
*: Liquid lipid amounts expressed as percentages of total lipid amounts.