Figure 5.

Effects of KGO ointment on Melanogenesis in Skin-Damage-Induced UVB Irradiation in Mice. To elucidate the whitening efficacy of KGO, the formation of melanin on 1st, 3rd, and 5th weeks of UVB irradiation was analysed by dividing the dorsal skin of HRM-2 mice into the left (untreated) and right (treated) sides. Images were taken on the (A) 1st week, (B) 3rd week, and (C) 5th week. Values in the bar graphs are ± SEM from three independent experiments. *** p < 0.001, ** p < 0.05, and * p < 0.01 when compared with the UVB control. The normal mice are abbreviated as HRM-2 N; the UVB control is abbreviated as UVB-C; sunblock is abbreviated as SB.