Figure 6.

KGO ointment on wrinkle formation in HRM-2 mice. To measure the effect of improving the wrinkle depth with KGO ointments, HRM-2 mice were exposed to UVB to induce photo aging. The skin wrinkle depth was analysed, and images were taken (A). Changes in the depth of the wrinkles on the 3rd, 4th, and 5th weeks of KGO ointment treatment were observed. Values in the bar graphs are ± SEM from the experiments repeated in triplicate. *** p < 0.001, ** p < 0.05, and * p < 0.01 when compared with the UVB control. (B) Wrinkle formation on the 3rd week of KGO ointment treatment. (C) Wrinkles formation on the 4th week of KGO treatment. (D) Wrinkle formation on the 5th week of KGO ointment treatment. The normal mice are abbreviated as HRM-2 N; the UVB control is abbreviated as UVB-C; sunblock is abbreviated as SB.