Table 2.
Top canonical pathways generated in IPA affected by proteins that were differentially expressed in the gut intestinal tract of day of hatch chicks when compared to the saline (S) control treatment. At 18 embryonic days, embryos were administered 200 μL of S, Citrobacter freundii (C), Citrobacter spp. (C2), or lactic acid bacteria (L) into the amnion.
| Ingenuity canonical pathways1 | Z-score3 |
P-value |
||||
|---|---|---|---|---|---|---|
| C | C2 | L | C | C2 | L | |
| Acute-phase response signaling | --2 | 2.00 | -- | 0.31 | <0.01 | 0.10 |
| Gluconeogenesis I | -- | -- | 2.00 | 0.10 | <0.01 | <0.01 |
| Nitric oxide signaling in the cardiovascular system | -- | -- | 2.00 | 0.09 | <0.01 | <0.01 |
| NRF24-mediated oxidative stress response | 2.00 | -- | -- | <0.01 | 0.01 | <0.01 |
1
Significane generated in IPA at P ≤ 0.05 from right-tailed Fisher exact test.
2
-- = Z-score was not provided, so no prediction could not be obtained.
3
All canonical pathways predicted to be activated (Z-score ≥ 2.00) or inhibited (Z-score ≤ −2.00).
4
Nuclear factor erythroid 2-related factor 2.