Table 4.
miRNAs that have been reported to have a regulatory role during IBDV, IBV, Rev-T, DTMUV, or DEV infection.
| miRNA | Virus | Species | Source | Pattern | Targets | Cell function | Reference |
|---|---|---|---|---|---|---|---|
| let-7g | IBDV | Chicken | Bone marrow dendritic cells | Up | - | - | Lin et al., 2016 |
| miR-1635 | IBDV | Chicken | Bone marrow dendritic cells | Up | - | - | Lin et al., 2016 |
| miR-196-2 | IBDV | Chicken | Bone marrow dendritic cells | Down | - | - | Lin et al., 2016 |
| miR-21 | IBDV | Chicken | Cell lines | Up | VP1 | Suppress replication of IBDV | Wang, Ouyang, Pan, Wang, Xia, Bi, Wang and Wang, 2013b |
| miR-9* | IBDV | Chicken | Cell lines | Up | IRF2 | Promote IBDV replication | Ouyang et al., 2015 |
| miR-1454 | IBV | Chicken | Kidney | Up/up/down | - | Associate with the virulence of IBV | Yang et al., 2017 |
| miR-7b | IBV | Chicken | Kidney | Up/up/down | - | Associate with the virulence of IBV | Yang et al., 2017 |
| miR-222b-3p | IBV | Chicken | Kidney | Up/up/up | - | Associate with the virulence of IBV | Yang et al., 2017 |
| miR-1563 | IBV | Chicken | Kidney | Down/up/up | - | Associate with the virulence of IBV | Yang et al., 2017 |
| miR-1723 | IBV | Chicken | Kidney | Down/up/down | - | Associate with the virulence of IBV | Yang et al., 2017 |
| miR-1782 | IBV | Chicken | Kidney | Up/down/down | - | Associate with the virulence of IBV | Yang et al., 2017 |
| miR-202-5p | IBV | Chicken | Kidney | Up/up/up | - | Associate with the virulence of IBV | Yang et al., 2017 |
| miR-6516-3p | IBV | Chicken | Kidney | Up/up/up | - | Associate with the virulence of IBV | Yang et al., 2017 |
| miR-155 | REV-T | Chicken | Cell lines | Up | JARID2 | Promotes cell survival | Bolisetty et al., 2009 |
| miR-155 | REV-T | Chicken | Cell lines | Up | - | - | Yao et al., 2017 |
| miR-7 | DTMUV | Duck | DEF | Up | - | - | Cui et al., 2018 |
| miR-133a-3p | DTMUV | Duck | DEF | Down | - | - | Cui et al., 2018 |
| miR-222a | DTMUV | Duck | DEF | Up | - | - | Cui et al., 2018 |
| miR-206 | DTMUV | Duck | DEF | Down | - | - | Cui et al., 2018 |
| miR-146b-5p | DTMUV | Duck | DEF | Up | - | - | Cui et al., 2018 |
| miR-1662 | DTMUV | Duck | DEF | Down | - | - | Cui et al., 2018 |
| miR-155 | DTMUV | Duck | DEF | Up | - | - | Cui et al., 2018 |
| miR-1a-3p | DTMUV | Duck | DEF | Down | - | - | Cui et al., 2018 |
| miR-221-3p | DTMUV | Duck | DEF | Up | - | - | Cui et al., 2018 |
| miR-133a-3p | DEV | Duck | DEF | Up | - | - | Wu et al., 2018 |
| let-7a-2-3p | DEV | Duck | DEF | Up | - | - | Wu et al., 2018 |
| miR-148a-5p | DEV | Duck | DEF | Up | - | - | Wu et al., 2018 |
| miR-34c-5p | DEV | Duck | DEF | Up | - | - | Wu et al., 2018 |
| miR-1a-3p | DEV | Duck | DEF | Up | - | - | Wu et al., 2018 |
| miR-20b-3p | DEV | Duck | DEF | Down | - | - | Wu et al., 2018 |
| miR-125-2-3p | DEV | Duck | DEF | Down | - | - | Wu et al., 2018 |
| miR-215-5p | DEV | Duck | DEF | Down | - | - | Wu et al., 2018 |
| miR-2954-5p | DEV | Duck | DEF | Down | - | - | Wu et al., 2018 |
| miR-29b-1-5p | DEV | Duck | DEF | Down | - | - | Wu et al., 2018 |
| miR-D25-5p | DEV | DEV | DEF | Up | - | - | Wu et al., 2018 |
| miR-D2-3p | DEV | DEV | DEF | Up | - | - | Wu et al., 2018 |
| miR-D26-5p | DEV | DEV | DEF | Up | - | - | Wu et al., 2018 |
| miR-D27-5p | DEV | DEV | DEF | Up | - | - | Wu et al., 2018 |
| miR-D28-3p | DEV | DEV | DEF | Up | - | - | Wu et al., 2018 |
| miR-D29-5p | DEV | DEV | DEF | Up | - | - | Wu et al., 2018 |
| miR-D30-3p | DEV | DEV | DEF | Up | - | - | Wu et al., 2018 |
| miR-D31-3p | DEV | DEV | DEF | Up | - | - | Wu et al., 2018 |
Abbreviations: DEF, duck embryonic fibroblasts; DEV, duck enteritis virus; DTMUV, Duck Tembusu virus; IBDV, infectious bursal disease virus; IBV, infectious bronchitis virus.