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. 2020 Jan 22;99(3):1491–1501. doi: 10.1016/j.psj.2019.11.008

Table 2.

Summary of conditions applied for characterization of studied food industry by-products by HPLC.

Extracts
RL
RH
GS
P
HYT
H
Solvent MeOH Water MeOH DMSO DMSO DMSO
Dilution (mg/ml) 0.2–4 5 3 4 5 5
Temperature (ºC) 30 30 30 30 30 30
Flow rate (ml/min) 0.75 1 1 1 1 1
Mobile phase Acetonitrile (65%), water (35%), and phosphoric acid (0.2%) Acetonitrile (65%), water (35%), and phosphoric acid (0.2%) (A) Acetic acid/water (1:99) and (B) acetonitrile (A) Acetic acid/water (0.1:99.5) and (B) methanol (A) Acetic acid/water (2.5:97.5) and (B) acetonitrile (A) Methanol and (B) water (50:50 v/v)
Linear gradient - - From 96% (A) and 4% (B) to 90% (A) in 25 min; changing to 87% (A) in 5 min; changing to 50% (A), before re-equilibrating in 10 min 15 min with 100% (A) was followed by a linear gradient from 100% (A) to 90% (A) and 10% (B) in 15 min; 10 min maintained before equilibration in 10 min to the initial composition From 95% (A) and 5% (B) to 75% (A) and 25% (B) in 20 min; changing to 50% (A) and (B) in 20 min; changing to 20% (A) and 80% (B), and re-equilibrated in 10 min -
Total time (min) 25 25 45 50 60 25
Wavelength (nm) 230 340 280 280 280 280

Abbreviations: DMSO, dimethyl sulfoxide; GS, grape seed; H, Harpagophytum; HPLC, high-performance liquid chromatography; HYT, hydroxytyrosol; MeOH, methanol; P, pomegranate; RH, rosemary extract; RL, rosemary extract (Nutrox OS).