Table 3.
Effect of PaLE (i.p.) on the consumption of water, feed and organ mass of mice without and with S180 tumor.
| Parameters | Healthy | Animal with Tumor | |||
|---|---|---|---|---|---|
| Saline | Saline |
PaLE 100 mg/kg/day |
PaLE 150 mg/kg/day |
5-FU 25 mg/kg/day |
|
| Water consumption (mL) | 46.2 ± 1.33 | 41.3 ± 3.70 | 41.60 ± 0.93 | 40.90 ± 1.10 | 15.60 ± 0.40 * # |
| Feed Consumption (g) | 37.05 ± 0.38 | 35.60 ± 0.63 | 28.35 ± 0.42 * # | 27.95 ± 0.95 * # | 17.95 ± 0.78 * # |
| Spleen (g/100 g m.c.) | 0.39 ± 0.01 * | 0.52 ± 0.03 | 0.64 ± 0.02 * # | 0.62 ± 0.04 * # | 0.29 ± 0.03 * # |
| Liver (g/100 g m.c.) | 5.33 ± 0.12 | 5.41 ± 0.08 | 5.64 ± 0.20 | 5.88 ± 0.15 | 5.33 ± 0.09 |
| Kidneys (g/100 g m.c.) | 1.35 ± 0.03 | 1.44 ± 0.06 | 1.33 ± 0.04 | 1.38 ± 0.04 | 1.40 ± 0.05 |
The data are presented as the mean ± the standard error of the mean of 10 animals. The results were evaluated by one-way ANOVA followed by Student Newman Keuls post-test. * p < 0.05 compared to the group of animals with tumor, treated with saline; # p < 0.05 compared to the group of healthy animals, treated with saline. Saline was used with negative control and 5-FU as positive control.