Figure 3.

(a) RP-HPLC profiles of Acm₂-precursor peptide and the reaction solutions after I₂-oxidation in 50% MeOH at pH 2, pH 7, and pH 9 with a linear gradient from 10 to 50% CH₃CN in 40 min (l.0%/min). (b) RP-HPLC profiles of Acm₂-precursor peptide and the reaction solutions after I₂-oxidation in 50% tetrahydrofuran (THF) at 25–80 °C with a linear gradient from 10 to 40% CH₃CN in 60 min (0.5%/min) after 10 min of injection.