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. 2020 Oct 20;25(20):4815. doi: 10.3390/molecules25204815

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Rb3 attenuated P. gingivalis LPS-induced osteoclast differentiation and bone resorption in rats. (A) ABL was compared from H&E staining slides. Black triangles represent CEJ, and distance from CEJ to AC was measured between first-second molars of rats. (B) Tartrate-resistant acid phosphatase (TRAP) staining for maxilla slides of rats. Red staining cells (arrows) are osteoclasts and their immediate precursors. (C) ABL were calculated and presented in bar graph. (D) Osteoclasts were enumerated and presented in bar graph. Data were presented as means ± SE (n = 4 rats/group). * p < 0.05 versus LPS group. CEJ, cemento-enamel junction; ABL, alveolar bone loss; AC, alveolar bone; SE, standard error.