Table 5.

Univariate and Multivariate Analysis of Factors Associated With Increased Odds of Adverse Events at 30 Days in Patients With COVID-19 in the Critical Care Setting

	Univariate		Multivariate
	OR	95% CI	Adjusted OR	95% CI
Major arterial or venous thromboembolic event
Age	0.98	0.96–1.00	0.97	0.95–0.99
Male	1.33	0.69–2.58	1.31	0.64–2.71
VTE prophylaxis	1.47	0.5–4.35	0.76	0.22–2.57
ARDS	8.14	2.38–27.87	6.69	1.85–24.14
D-dimer (decile)	1.13	1.0–1.29	1.17	1.03–1.33
Major cardiovascular event
Age	1.01	0.99–1.03	1.00	0.98–1.03
Male	1.92	1.02–3.64	2.07	1.03–4.16
VTE prophylaxis	1.07	0.4–2.85	0.58	0.18–1.90
ARDS	7.42	2.72–20.25	5.79	2.01–16.69
D-dimer (decile)	1.13	1.01–1.27	1.12	0.99–1.27
History of CAD	0.68	0.3–1.53	0.71	0.27–1.85
Symptomatic VTE
Age	0.98	0.96–1.01	0.97	0.95–1.0
Male	1.63	0.76–3.49	1.54	0.69–3.44
VTE prophylaxis	6.07	0.78–47.1	2.51	0.41–15.44
ARDS	32.4	1.87–562.29	24.39	1.50–398.00
D-dimer (decile)	1.10	0.97–1.25	1.11	0.97–1.27
Death
Age	1.08	1.04–1.11	1.08	1.05–1.12
Male	1.82	0.83–3.95	1.91	0.78–4.64
VTE prophylaxis	0.44	0.16–1.21	0.63	0.18–2.22
ARDS	2.94	0.97–8.89	3.23	0.87–12.06
D-dimer (decile)	1.04	0.91–1.18	0.93	0.80–1.09
History of CAD	1.95	0.82–4.63	1.09	0.38–3.16

CAD = coronary artery disease; CI = confidence interval; OR = odds ratio; other abbreviations as in Tables 1, 2, and 3.