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. 2020 Oct 26;11(1):1466–1481. doi: 10.1080/21505594.2020.1838741

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© 2020 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Transcriptional comparison of C. auris AR0390 treated with aprepitant (APR), itraconazole (ITC), or a combination of both versus the untreated control. (a) Heat map of FPKM values of DEGs of each treatment versus the untreated control, scaled by row. (b) Volcano blot of DEGs from C. auris AR0390 treated with aprepitant/itraconazole (APR/ITC) at 10/1 µg/ml. (c) Volcano blot of DEGs from C. auris AR0390 treated with aprepitant (APR) at 10 µg/ml. (d) Volcano blot of DEGs from C. auris AR0390 treated with itraconazole (ITC) at 1 µg/ml. Significant down-regulated DEGs are shown in green, whereas significant up-regulated DEGs are shown in red