Figure 5.

Probiotic intake may prevent necrotizing enterocolitis by interfering with pathobionts. (a) Monthly NEC-incidence during the 2-year study period among all preterm born neonates (n = 179, gestational age<32 weeks) stratified according to supplementation group. In total, 9, 1, and 0 NEC cases were diagnosed in the control group, P1 group and P2 group, respectively. (b) SparCC correlation network analyses with genera at T1 in the probiotic 1 supplemented, (c) and probiotic 2 supplemented neonates as compared to control neonates (correlation >0.3, p < 0.05). Blue circles indicate genera with an increased abundance in probiotic groups, while red circles represent genera enriched in control neonates. Red lines indicate negative correlations, while blue lines indicate positive correlations