Table 3. Patient characteristics by primary outcome and group.
Success ( n = 40) | Failure ( n = 23) | p -Value | ||
---|---|---|---|---|
Age, mo (IQR) | All | 2.79 (1.29–5.78) | 2.62 (1.14–3.76) | 0.63 |
CPAP | 2.43 (1.04–3.18) | 2.15 (0.69–4.47) | 0.98 | |
HFNC | 4.26 (1.38–6.76) | 2.93 (1.40–4.26) | 0.21 | |
Weight, kg (SD) | All | 5.73 (1.69) | 5.69 (1.55) | 0.94 |
CPAP | 5.24 (1.3) | 5.94 (1.76) | 0.24 | |
HFNC | 6.13 (1.9) | 5.51 (1.40) | 0.31 | |
mWDS (IQR) | All | 5 (4–6) | 5 (4–6) | 0.58 |
CPAP | 4.5 (4–5) | 5 (4–6.25) | 0.34 | |
HFNC | 5 (4–6) | 5 (4–6.5) | 0.93 | |
PIM-2 score, % (IQR) | All | 0.7 (0.3–1.1) | 0.9 (0.8–1.1) | 0.06 |
CPAP | 0.65 (0.28–1.13) | 0.95 (0.80–1.32) | 0.05 | |
HFNC | 0.7 (0.3–1.1) | 0.9 (0.7–1.05) | 0.45 | |
RR, breaths/min (SD) | All | 46.95 (12.42) | 50.48 (12.97) | 0.15 |
CPAP | 45.22 (13.93) | 50.2 (16.49) | 0.40 | |
HFNC | 48.36 (11.17) | 50.69 (10.22) | 0.54 | |
HR, beats/min (SD) | All | 149.68 (20.05) | 149.91 (22.25) | 0.48 |
CPAP | 155.78 (18.99) | 146.4 (15.33) | 0.19 | |
HFNC | 144.68 (19.91) | 152.62 (26.7) | 0.32 | |
SpO 2 , % (IQR) | All | 97 (96–98) | 99 (96.5–99.25) | 0.11 |
CPAP | 97 (96–98.25) | 99 (98.5–99.5) | 0.05 | |
HFNC | 97 (95–98.5) | 98 (94.5–99.5) | 0.57 | |
FiO 2 (IQR) | All | 0.4 (0.35–0.5) | 0.38 (0.3–0.44) | 0.32 |
CPAP | 0.4 (0.35–0.5) | 0.35 (0.3–0.5) | 0.33 | |
HFNC | 0.4 (0.38–0.5) | 0.35 (0.3–0.4) | 0.28 | |
PICU LOS, d (IQR) | All | 5 (4–6) | 7 (5–11) | 0.01 |
CPAP | 4.5 (3.75–6.25) | 5.4 (4.75–11.25) | 0.04 | |
HFNC | 5 (3.75–6.25) | 8 (4.5–12.5) | 0.03 | |
Hosp LOS, d (IQR) | All | 8 (6.25–10) | 12 (8–17) | <0.001 |
CPAP | 8 (7–10) | 10.5 (7.75–14) | 0.09 | |
HFNC | 7 (6–9.25) | 12 (9–17.5) | 0.002 |
Abbreviations: CPAP, continuous positive airway pressure; FiO2, fraction of inspired oxygen; HFNC high-flow nasal cannula; Hosp; hospital; HR, heart rate; LOS, length of stay; mWDS, modified Wood–Downes score; PICU, pediatric intensive care unit; RR, respiratory rate; SpO2, peripheral capillary oxygen saturation.
Note: Data are mean and standard deviation (SD), median and interquartile range (IQR), or count ( n ) and percentage (%).