Fig. 1.

The pharmacokinetic study of baicalein and the comparison between crystal form α and β. (A) Scanning electron micrographs (SEM) of crystal forms α and β of baicalein. (B) Chemical structure of baicalein and baicalin. (C) Plasma concentration–time curve of baicalein after oral administration of crystal forms α and β of baicalein (200 mg/kg) in rats (n = 10). (D) Plasma concentration–time curve of baicalin after oral administration of crystal forms α and β of baicalein (200 mg/kg) in rats (n = 10). (E) Plasma concentration–time curve of baicalein and baicalin after intravenous injection of baicalein (10 mg/kg) in rats (n = 10). Results were shown as mean + SD.