Fig. 5.
Effect of chrysin on the histopathology of adipose tissue of rats fed a high fructose diet. The tissue samples were stained with hematoxylin and eosin and observed at a magnification of 400× (a) Adipose tissue from rats provided with normal chow and water showing normal adipocytes, (b) Adipose tissue from rats provided with high fructose diet (HFD) alongwith the normal chow showing enlarged adipocytes and mild inflammation compared to normal control, (c) Adipose tissue from rats on HFD treated with orlistat for 8 weeks, (d) Adipose tissue from rats on HFD treated with chrysin 25 mg/kg for 8 weeks, (e) Adipose tissue from rats on HFD treated with chrysin 50 mg/kg for 8 weeks, (f) Adipose tissue from rats on HFD treated with chrysin 100 mg/kg for 8 weeks, (g) Number of adipocytes per high power field in the adipose tissue of rats in the different groups. Data was analyzed by one-way ANOVA followed by Tukey's multiple comparison test. Values are expressed as mean ± SEM (n = 8 per group) (*p < 0.05 vs NC; #p < 0.05 vs HFD). Abbreviations: A-adipocytes, I-mild inflammation.