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. 2020 Oct 26;10:18289. doi: 10.1038/s41598-020-74050-8

Table 1.

Characterization of the WSPs detected in genomes of SARS-CoV-2.

Segment ID Segment positiona (begin–end) WSPsb nt mutation (# isolates) Position in the codon #codon Amino acid
S2 2899–3179 nsp3-[3,037] U (184)/C (409) Third 106 Phenylalanine/Phenylalanine
S4 8639–8919 nsp4-[8,782] U (183)/C (410) Third 76 Serine/Serine
S6 10,959–11,219 nsp6-[11,083] C (1)/U (99)/G (493) Third 37 Phenylalanine/Phenylalanine/Leucine
S8 14,259–14,539 nsp12-[14,408] U (184)/C (409) Second 323 Leucine/Proline
S10 17,600–18,200 nsp13-[17,747] U (101)/C (492) Second 504 Leucine/Proline
nsp13-[17,858] G (101)/A (492) Second 541 Cysteine/Tyrosine
nsp14-[18,060] U (105)/C (488) Third 7 Leucine/Leucine
S12 23,270–23,550 S-[23,403] G (185)/A (408) Second 614 Glycine/Aspartate
S14 28,004–28,285 ORF8-[28,144] C (184)/U (409) Second 84 Serine/Leucine
S16 28,745–29,025 N-[28,881] A (60)/G (533) Second 203 Lysine/Arginine
N-[28,882] A (60)/G (533) Third
N-[28,883] C (60)/G (533) First 204 Glycine/Arginine

aRelative to the multiple sequence alignment constructed for full-length genomes.

bWidely shared polymorphism (WSP) positions are relative to the reference genome (GISAID accession ID: EPI_ISL_402124).