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. 2020 Oct 26;10:18275. doi: 10.1038/s41598-020-75104-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Differentially expressed genes in the endometrium at 7 days postpartum (DPP) in cows with ‘pathological’ inflammation (PATH; ≥ 18% PMN, n = 4) which had developed CYTO by 21 DPP relative to cows with similar levels of inflammation but which remained healthy (PHYS; ≥ 18% PMN, n = 5). A. PCA plot shows distribution of RNA-seq samples, where colours indicate the two groups and numbers refer to specific cow IDs (as detailed in Supplementary Table S1). B. Gene expression data is presented as a volcano plot using log values of the fold change and p value. Each data point represents a single gene, with those in black representing genes that survived the cut off thresholds of adjusted p < 0.05 and FC > 1. The 20 most significant differentially expressed genes are labelled, where gene names are available.