Table 2.

Crude and adjusted odd ratios (95% confidence interval) for Meniere’s disease in levothyroxine, goiter, hypothyroidism, thyroiditis, hyperthyroidism, and autoimmune thyroiditis.

Characteristics	Odd ratios for Meniere’s disease
	Crudea	P value	Model 1a,b	P value	Model 2a,c	P value
Total participants (n = 40,915)
Levothyroxine	1.27 (1.12–1.44)	< 0.001*	1.28 (1.09–1.50)	0.003*	0.94 (0.76–1.16)	0.583
Goiter	1.37 (1.23–1.53)	< 0.001*	1.28 (1.13–1.45)	< 0.001*	1.19 (1.04–1.36)	0.011*
Hypothyroidism	1.34 (1.19–1.51)	< 0.001*	1.34 (1.17–1.53)	< 0.001*	1.21 (1.02–1.44)	0.030*
Thyroiditis	1.35 (1.14–1.61)	< 0.001*	1.23 (1.01–1.49)	0.041*	1.05 (0.85–1.29)	0.667
Hyperthyroidism	1.47 (1.28–1.69)	< 0.001*	1.37 (1.18–1.60)	< 0.001*	1.27 (1.09–1.49)	0.003*
Autoimmune thyroiditis	1.49 (1.15–1.92)	0.002*	1.26 (0.94–1.69)	0.122

CCI Charlson Comorbidity Index.

*Conditional logistic regression model, significance at P < 0.05.

^aModels stratified by age, sex, income, and region of residence.

^bModel 1 was adjusted for obesity, smoking, alcohol consumption, benign paroxysmal vertigo, vestibular neuronitis, other peripheral vertigo, thyroid cancer, and CCI scores.

^cModel 2 was adjusted for model 1 plus levothyroxine, goiter, hypothyroidism, thyroiditis, hyperthyroidism.