Table 2.
The Ascites and Serum Tumor Marker Levels in Gastrointestinal and Ovarian Cancer Patients
| Characteristics (N=102) | Ascites CEA | P-value | Serum CEA | P-value | Ascites CA19-9 | P-value | Serum CA19-9 | P-value | Ascites CA125 | P-value | Serum CA125 | P-value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Peritoneal metastasis | ||||||||||||
| Positive | 137.90(0.24–1000.00) | 0.15a | 20.40(0.25–1000.00) | 0.88a | 180.91(0.60–10,000.00) | 0.06a | 53.91(0.60–10,000.00) | 0.82a | 638.73 (72.98–5000.00) | <0.001a | 258.92(28.45–5000.00) | 0.22a |
| Negative | 79.72(0.20–497.54) | 17.70(0.50–290.80) | 55.25(0.60–917.50) | 32.34(0.60–1396.00) | 372.01(35.89–1850.00) | 161.82(48.02–855.62) | ||||||
| Tumor stage(TNM) | ||||||||||||
| III | 17.98 (0.20–871.56) | 0.13a | 10.29 (0.25–290.80) | 0.48a | 31.25 (0.60–917.50) | 0.06a | 27.03(0.60–1396.00) | 0.35a | 490.79 (35.89–5000.00) | 0.20a | 158.90 (48.02–2501.00) | 1.00a |
| IV | 127.58 (0.24–1000.00) | 25.78 (0.28–1000.00) | 202.21 (0.60–10,000.00) | 68.07(0.60–10,000.00) | 589.00 (72.98–5000.00) | 233.20 (28.45–5000.00) | ||||||
| Histologic differentiation | ||||||||||||
| Well | 80.89 (0.35–871.56) | 0.57b | 23.47(0.25–290.80) | 0.97b | 50.66 (0.60–917.50) | 0.54b | 43.79 (0.60–1396.00) | 0.96b | 440.50 (69.85–3547.50) | 0.78b | 143.60 (89.20–579.86) | 0.52b |
| Moderate | 91.00 (0.20–1000.00) | 17.70(0.28–877.20) | 119.31 (0.60–10,000.00) | 32.34 (0.60–9903.00) | 519.54 (35.89–5000.00) | 189.37 (28.45–1007.00) | ||||||
| Poor | 127.58 (0.33–1000.00) | 15.02(0.33–1000.00) | 161.48 (2.12–10,000.00) | 41.25 (1.64–10,000.00) | 593.50 (74.58–5000.00) | 270.56 (32.56–5000.00) | ||||||
| Liver metastasis | ||||||||||||
| Positive | 135.51 (0.33–1000.00) | 0.07a | 32.44 (0.28–1000.00) | 0.21a | 202.86 (1.20–10,000.00) | 0.05a | 64.86 (1.29–9903.00) | 0.38a | 591.25 (89.66–5000.00) | 0.27a | 195.03 (28.45–5000.00) | 0.18a |
| Negative | 19.93 (0.20–1000.00) | 12.13 (0.25–290.80) | 31.68 (0.60–10,000.00) | 30.18 (0.60–10,000.00) | 484.85 (35.89–5000.00) | 250.73 (48.02–2501.00) | ||||||
| Ascites volume | ||||||||||||
| 1500–3000mL | 84.21 (0.20–1000.00) | 0.76a | 11.30 (0.50–877.20) | 0.56a | 138.73 (0.60–6213.00) | 0.45a | 41.27 (0.60–5371.00) | 0.64a | 445.87 (69.85–5000.00) | 0.04a | 158.90 (28.45–1622.00) | 0.13a |
| Over 3000mL | 104.20 (0.24–1000.00) | 23.69 (0.25–1000.00) | 116.11 (1.00–10,000.00) | 32.71 (0.60–10,000.00) | 597.38 (35.89–5000.00) | 267.08 (32.56–5000.00) |
Notes: aMann–Whitney U-test; bKruskal–Wallis H-test. P<0.05.