Table 3.
The Ascites and Serum Tumor Marker Levels in Gastrointestinal Cancer Patients
| Characteristics (N=70) | Ascites CEA | P-value | Serum CEA | P-value | Ascites CA19-9 | P-value | Serum CA19-9 | P-value | Ascites CA125 | P-value | Serum CA125 | P-value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Peritoneal metastasis | ||||||||||||
| Positive | 278.50(0.63–1000.00) | 0.001a | 45.76(0.77–1000.00) | 0.19a | 310.86(0.60–10,000.00) | 0.002a | 142.40(0.60–10,000.00) | 0.08a | 563.95(72.98–2954.00) | 0.001a | 190.05 (28.45–847.10) | 0.22a |
| Negative | 118.50 (0.20–497.54) | 29.90(0.94–290.80) | 155.91(0.60–917.50) | 74.50(0.60–1396.00) | 272.85(35.89–843.20) | 131.78 (48.02–584.20) | ||||||
| Tumor stage(TNM) | ||||||||||||
| III | 145.69 (0.20–871.56) | 0.17a | 37.15 (1.36–290.80) | 0.66a | 150.33 (0.60–917.50) | 0.13a | 49.47 (0.60–1396.00) | 0.36a | 314.89 (35.89–698.20) | 0.06a | 135.00 (48.02–584.20) | 0.48a |
| IV | 223.63 (0.63–1000.00) | 41.13 (0.77–1000.00) | 289.15 (0.60–10,000.00) | 134.12 (0.60–10,000.00) | 515.52 (72.98–2954.00) | 189.54 (28.45–847.10) | ||||||
| Histologic differentiation | ||||||||||||
| Well | 90.54 (0.35–871.56) | 0.32b | 48.78 (1.43–290.80) | 0.59b | 159.60 (0.60–917.50) | 0.39b | 108.90 (0.60–1396.00) | 1.00b | 402.65 (69.85–1217.00) | 0.47b | 135.00 (89.20–391.40) | 0.38b |
| Moderate | 172.26 (0.20–1000.00) | 39.83 (0.77–877.20) | 227.92 (0.60–10,000.00) | 122.64 (0.60–9903.00) | 449.41 (35.89–1841.00) | 140.32 (28.45–584.20) | ||||||
| Poor | 221.23 (0.63–1000.00) | 34.98 (0.94–1000.00) | 297.89 (2.12–10,000.00) | 127.46 (1.64–10,000.00) | 497.47 (74.58–2954.00) | 199.50 (41.95–847.10) | ||||||
| Liver metastasis | ||||||||||||
| Positive | 221.23 (0.63–1000.00) | 0.62a | 48.88 (0.77–1000.00) | 0.72a | 289.15 (2.12–10,000.00) | 0.24a | 134.12 (1.64–9903.00) | 0.72a | 341.36 (35.89–2954.00) | 0.05a | 165.90 (28.45–382.10) | 0.61a |
| Negative | 169.32 (0.20–1000.00) | 37.15 (1.36–290.80) | 202.21 (0.60–10,000.00) | 119.64 (0.60–10,000.00) | 541.98 (89.66–1841.00) | 154.24 (48.02–847.10) | ||||||
| Ascites volume | ||||||||||||
| 1500–3000mL | 144.05 (0.20–1000.00) | 0.20a | 29.90 (0.77–877.20) | 0.11a | 288.03 (0.60–6213.00) | 0.42a | 122.64 (0.60–5371.00) | 0.93a | 388.94 (69.85–1764.00) | 0.16a | 133.35 (28.45–501.32) | 0.07a |
| Over 3000mL | 227.42 (0.63–1000.00) | 48.78 (0.94–1000.00) | 214.43 (1.34–10,000.00) | 118.18 (1.64–10,000.00) | 504.01 (35.89–2954.00) | 200.38 (44.48–847.10) |
Notes: aMann–Whitney U-test; bKruskal–Wallis H-test. P<0.05.