Table 2.

Description of the depression measures used in the selected studies.

Measure	Domains	Items	Scales	Focus
HAM-D (Hamilton M, J Neurol Neurosurg Psychiatry 1960) [43]	6 domains: anxiety/somatization, weight, cognitive disorders, diurnal variations, slowing down, sleep disorders	21 items	5-, 4- or 3-point scale	To assess the severity of depressive symptoms
HAMD17 (Hamilton M, J Neurol Neurosurg Psychiatry 1960) [43]	Brief version of the HAM-D	17 items	5- or 3-point scale	To assess the severity of depressive symptoms (Derived from the HAM-D)
BDI (Beck AT et al., Arch Gen Psychiatry 1961) [44]	21 domains: mood, pessimism, sense of failure, self-dissatisfaction, guilt, punishment, self-dislike, self-accusation, suicidal ideas, crying, irritability, social withdrawal, indecisiveness, body image change, work difficulty, insomnia, fatigability, loss of appetite, weight loss, somatic preoccupation, and loss of libido	21 items	4-point scale	To assess the severity of depressive symptoms in cognitive domains
MES (Bech P., Acta Psychiatr Scand 1980) [45]	11 domains: depressed mood, tiredness, work and interests, concentration difficulties, sleep disturbances, psychic anxiety, emotional introversion, worthless and guilt, suicidal thoughts, decreased verbal activity, and decreased motor activity	11 items	5-point scale	To assess depression severity and measure change in depressive states during treatment

HAM-D Hamilton Depression Scale.