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. 2020 Oct 22;14:4407–4422. doi: 10.2147/DDDT.S272877

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© 2020 Qin et al.

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Alprostadil injection suppressed CME-induced myocardial apoptosis. (A) Representative images of TUNEL staining, in which apoptotic nuclei were yellow-brown stained, while normal nuclei were blue stained (magnification ×400, scale bar=20 μm). The black arrow indicates apoptotic cells. (B) Relative TUNEL-positive nuclei in each group (n=6 per group). *P<0.05, compared with Sham group, ^#P<0.05, compared with CME group, ^aP<0.05, compared with High group.

Abbreviations: CME, coronary microembolization; Low, CME plus alprostadil injection (2 μg/kg); High, CME plus alprostadil injection (4 μg/kg).