a |
0.4 |
Proliferation rate of activated Tconvs |
molecule−1time−1
|
b |
0.1 |
Natural death rate of activated Tconvs and Tregs |
time−1
|
c |
|
Fratricide death rate of activated Tconvs |
cell−1time−1
|
d |
0.01 |
IL-2 secretion rate by activated Tconvs |
molecule cell−1time−1
|
e |
0.01 |
IL-2 consumption rate by activated Tconvs and Tregs |
cell−1time−1
|
f |
1 |
IL-2 decay rate |
time−1
|
g |
0.1 |
Natural death rate of naïve Tconvs and resting Tregs |
time−1
|
β |
0.05 |
Ag stimulation of naïve Tconvs and resting Tregs |
time−1
|
γ |
0.1 |
Treg-mediated suppression rate |
cell−1time−1
|
ε |
0.6 |
Ratio of proliferation rates of Tregs to Tconvs |
– |
λ |
0.006 |
Ratio of renewal rates of resting Tregs to naïve Tconvs |
– |
|
4 |
Renewal rate of naïve Tconvs |
cell time−1
|
|
|
Renewal rate of resting Tregs |
cell time−1
|