(8-oxodA) |
8-oxo-7,8-dihydro-20-deoxyadenosine |
(8-oxodG) |
8-oxo-7,8-dihydro-20-deoxyguanosine |
(AA) |
Aristolochic acid; Ascorbic acid |
(AGS) |
Aicardi–Goutieres syndrome |
(AhR) |
Aryl hydrocarbon receptor |
(AIM2) |
Absent in melanoma 2 |
(ALRs) |
AIM2-like receptors |
(AMPs) |
Antimicrobial peptides |
(AP) |
Apurinic/apyrimidinic |
(ATM) |
Ataxia telangiectasia mutated |
(ATR) |
ATM- and Rad3-Related complex |
(ATRIP) |
ATR interacting proteins |
(B reg) |
B regulatory cells |
(BRCA1/2) |
Breast Related Cancer Antigen 1/2 |
(CAD) |
Caspase-activated DNase |
(CAR-T) |
Chimeric Antigen Receptor T cell therapies |
(CCL2) |
C-C Motif Chemokine Ligand 2 |
(CD) |
Crohn’s disease |
(cGAMP) |
2′,3′-cyclic GMP-AMP |
(cGAS) |
Cyclic GMP-AMP synthase |
(CIN) |
Chromosome instability phenotype |
(cis- UCA) |
cis- urocanic acid |
(CLRs) |
C-type lectin receptors |
(CRI) |
Cancer related inflammation |
(CTLA-4) |
Cytotoxic T lymphocyte antigen 4 |
(CXCL8) |
C-X-C Motif Chemokine Ligand 8 |
(DAI) |
DNA-dependent activator of IFN regulatory factor |
(DAMPs) |
Damage-associated molecular patterns |
(DDR) |
DNA damage repair |
(DDX41) |
DExD/H-box helicase 41 |
(DNA-PK) |
DNA-dependent protein kinase |
(DR) |
Direct repair |
(DSBs) |
Double-strand breaks |
(dsDNA) |
Double-stranded DNAs |
(DSBR) |
Double-strand break repair |
(dsRNAs) |
Double-stranded RNAs |
(Erk) |
Extracellular signal-activated kinase |
(FA) |
Fanconi Anaemia repair complex |
(FICZ) |
6-formylindolo[3,2-b]carbazole |
(GG-NER) |
Global Genomic Repair |
(GSH) |
Glutathione |
(HAAs) |
Heterocyclic aromatic amines |
(HMGB1) |
High mobility group box 1 protein |
(HR) |
Homologous Recombination |
(HRD) |
Homologous recombination deficiency |
(ICAM-1) |
Intercellular adhesion molecule-1 |
(ICD) |
Immune cell death |
(ICIs) |
Immune checkpoint inhibitors |
(ICL) |
Interstrand crosslink repair |
(IFI16) |
Interferon gamma-inducible protein 16 |
(IFN) |
Interferon |
(IFN-γ) |
Interferon-gamma |
(IL-1) |
Interleukin-1 |
(IL-10) |
Interleukin-10 |
(IL-18) |
Interleukin-18 |
(IL-1β) |
Interleukin-1β |
(IL-4) |
Interleukin-4 |
(IL-6) |
Interleukin-6 |
(iNOS) |
Inducible nitric-oxide synthase |
(IR) |
Ionizing radiation |
(IRFs) |
IFN-regulatory factors |
(LET) |
Linear Energy Transfer |
(LOH) |
Loss of heterozygosity |
(LPS) |
Lipopolysaccharide |
(mAbs) |
Monoclonal antibodies |
(mDCs) |
Myeloid dendritic cells |
(MGMT) |
O6-methylguanine DNA methyltransferase |
(MH) |
Microhomology |
(MM) |
Malignant Mesothelioma |
(MMEJ) |
Microhomology Mediated End Joining |
(MMR) |
Mismatch Repair |
(MPM) |
Malignant pleural mesothelioma |
(mtDNA) |
Mitochondrial DNA |
(MyD88) |
Myeloid differentiation primary response gene 88 |
(NADPH) |
Nicotinamide adenine dinucleotide phosphate |
(NER) |
Nucleotide Excision Repair |
(NF-kB) |
Nuclear factor kappa B |
(NHEJ) |
Non-Homologous End Joining |
(NKT) |
Natural Killer T cells |
(NLRP3) |
NOD-, LRR- and pyrin domain-containing protein 3 |
(NLRs) |
NOD-like receptors |
(NRF2) |
NFE2-related factor 2 |
(OH·) |
Hydroxyl radicals |
(PAFs) |
Platelet- activating factors |
(PAHs) |
Polycyclic aromatic hydrocarbons |
(PAMPs) |
Pathogen-associated molecular patterns |
(PARP1) |
Poly-(ADP-ribose)-polymerase 1 |
(PARPi) |
PARP inhibitors |
(PD1) |
programmed cell death protein 1 |
(PDL1) |
programmed cell death ligand 1 |
(PRRs) |
Pattern recognition receptors |
(RANKL) |
Epidermal- derived receptor activator of nuclear factor-κB ligand |
(RIG-I) |
Retinoic acid-inducible gene-I |
(RLRs) |
Retinoic acid-inducible gene-I (RIG-I)-like receptors |
(RNS) |
Reactive nitrogen species |
(ROS) |
Reactive oxygen species |
(RPA) |
Replication Protein A |
(RT) |
Radiation Therapy |
(SASP) |
Senescence associated secretory phenotype |
(SDSA) |
Synthesis-dependent strand annealing repair |
(SLE) |
Systemic lupus erythematosus |
(SSA) |
Single Strand Annealing |
(SSBs) |
Single-strand breaks |
(ssDNA) |
Single-stranded DNA |
(STING) |
cGAS- sensor protein stimulator of IFN genes |
(STAT3) |
Signal Transducer And Activator Of Transcription 3 |
(TAI) |
Tumor allelic imbalance |
(TAMs) |
Tumor-associated macrophages |
(TBK1) |
TANK-binding kinase 1 |
(TC-NER) |
Transcription-Coupled Repair |
(TCR) |
Transcription-Coupled Repair |
(Th1) |
T helper 1 cells |
(Th17) |
T helper 17 cells |
(Th2) |
T helper 2 cells |
(TLRs) |
Toll-like receptors |
(TMB) |
Tumor mutational burden |
(TME) |
Tumor microenviroment |
(TNF-α) |
Tumor necrosis factor alpha |
(TRCs) |
Transcription-replication conflicts |
(Treg) |
T regulatory cells |
(TREX) 1 |
Three prime repair exonuclease |
(UVR) |
Ultraviolet radiation |
(Vit C) |
Vitamin C |