Table 2.

DFE exposure scenarios used in the PBPK simulations.

Subject/Scenario	Inhaled Concentration	Total Abuse Duration	Inhalation Duration	Inhalation Cycle
X	1,000,000 ppm	6 h	1.5–8 s	3–5 min
Y	1,000,000 ppm	2 h	5–15 s	2–5 min