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. 2020 Oct 13;21(20):7534. doi: 10.3390/ijms21207534

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Metabolism and differentiation are coupled during neurulation. (A) Differential expression of ectoderm derived cell populations grouped together and compared to the non-ectoderm-derived cells at E8.25. (B) Bar plot showing the top up- and downregulated genes at E8.25. Arrows point out metabolic genes. (C) Dot plot showing molecular gene ontology of differentially expressed genes at E8.25. (D) Differential expression of ectoderm-derived cell populations grouped together and compared to the non-ectoderm-derived cells at E9.5. (E) Bar plot showing top up- and downregulated genes at E9.5. Arrows point out metabolic genes. (F) Dot plot showing molecular gene ontology analysis of differentially expressed genes at E9.5.