FIGURE 2.

Recordings of contractile responses of two saphenous artery segments to methoxamine in a 12‐day‐old rat. The first concentration–response relationships (left panels in a and b) are similar for the two arterial segments. Application of the TASK‐1 channel blocker AVE1231 (1 μmol·L⁻¹) causes an increase in basal tone and of the contractile responses to methoxamine (a), while incubation with an equivalent volume of the solvent (5‐μl DMSO per 5‐ml myograph chamber) does not affect the level of basal tone and the contractile response (b). W, washout