FIGURE 5.
The effects of AVE1231 on force and membrane potential in arterial smooth muscle of two age groups. (a, b) The values of force at baseline (Bl2, corresponds to Baseline 2 in Figure 4), solvent (DMSO) or TASK‐1 channel blocker (AVE1231, 1 μmol·L−1), and under the combination of methoxamine (MX) and solvent (DMSO + MX) or AVE1231 (AVE1231 + MX) in saphenous arteries of adult (a; n = 7, 7) and young rats (b; n = 6, 10), respectively. (c, d) The corresponding values of membrane potential in arteries of adult (c) and young (d) rats, respectively. Data are presented as the median and interquartile range. # P < 0.05 between time‐control and AVE1231 application (Mann–Whitney U test)