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. 2020 Oct 26;78(1):1–14. doi: 10.1001/jamaneurol.2020.3753

Table 1. Clinical Characteristics of FNDs vs Other Neurological Disorders in Adult and Pediatric ED Visits Comparing FNDs With Other Neurological Disordersa.

Variable Adult ≥18 y (2017 NEDS) subpopulation (n = 118 034 396) Pediatric 5-17 y (2017 NEDS) subpopulation (n = 15 522 879)
FND, No./total No. (%) (n = 36 359) Non-FND, No./total No. (%) (n = 8 625 167) P valueb FND, No./total No. (%) (n = 3800) Non-FND, No./total No. (%) (n = 328 609) P valueb
Age, median (IQR), y 40.47 (27.76-53.83) 58.06 (40.64-74.48) <.001 14.56 (12.14-15.84) 12.58 (9.00-15.18) <.001
Age category, y
5-12 NA NA <.001 914 (24.1) 150 564 (45.8) <.001
13-17 NA NA 2886 (75.9) 178 045 (54.2)
18-40 17 921 (49.3) 2 096 401 (24.3) NA NA
41-65 14 022 (38.6) 3 112 025 (36.1) NA NA
>65 4416 (12.2) 3 416 740 (39.6) NA NA
Sex
Female 25 807 (71.0) 5 114 253 (59.3) <.001 2733 (71.9) 178 615 (54.4) <.001
Male 10 547 (29.0) 3 510 535 (40.7) 1067 (28.1) 149 972 (45.6)
Socioeconomic status
Zip code income quartile, percentile
0-25th, Lowest 13 281/35 697 (37.2) 2 742 215/8 479 643 (32.3) <.001 1257/3705 (33.9) 108 271/324 938 (33.3) .61
26th-50th 10 304/35 697 (28.9) 2 271 692/8 479 643 (26.8) 1055/3705 (28.5) 86 701/324 938 (26.7)
51st-75th 7464/35 697 (20.9) 1 909 556/8 479 643 (22.5) 824/3705 (22.2) 73 418/324 938 (22.6)
76th-100th, Highest 4648/35 697 (13.0) 1 556 180/8 479 643 (18.4) 569/3705 (15.4) 56 548/324 938 (17.4)
Psychiatric comorbidity
Any psychiatric disorder 17 441 (48.0) 2 229 382 (25.9) <.001 1385 (36.4) 24 035 (7.3) <.001
Mood disorder 11 248 (30.9) 1 501 542 (17.4) <.001 733 (19.3) 14 986 (4.6) <.001
Anxiety disorders 10 660 (29.3) 1 200 518 (13.9) <.001 1029 (27.1) 14 109 (4.3) <.001
Associated functional conditions
FSDs 2588 (7.1) 281 401 (3.3) <.001 94 (2.5) 1497 (0.5) .001
Discharge disposition
Home 18 082 (49.7) 4 386 370 (50.9) <.001 2682 (70.6) 261 575 (79.6) <.001
Transfer to short-term hospital 265 (0.7) 177 548 (2.1) 81 (2.1) 11 067 (3.4)
Transfer to other facility or rehabilitation 718 (2.0) 215 749 (2.5) 69 (1.8) 3301 (1.0)
Home with home health care 179 (0.5) 62 684 (0.7) ≤10 278 (0.1)
Against medical advice 576 (1.6) 81 224 (0.9) ≤10 854 (0.3)
Admitted to inpatient 16 457 (45.3) 3 675 531 (42.6) 952 (25.1) 50 666 (15.4)
Died in ED ≤10 8538 (0.1) <.001 0 218 (0.1) <.001
Died in hospitalc 202 (0.6) 117 795 (1.4) <.001 0 477 (0.2) <.001
Primary insurance payer
Medicare 11 395/36 124 (31.6) 4 337 785/8 604 396 (50.4) <.001 ≤10 1030/327 786 (0.3) .006
Medicaid 12 013/36 124 (33.3) 1 700 281/8 604 396 (19.8) 2027 (53.4) 185 120/327 786 (56.5)
Private insurance 8070/36 124 (22.3) 1 766 219/8 604 396 (20.5) 1512 (39.9) 121 215/327 786 (37.0)
Self-pay 3226/36 124 (8.9) 556 225/8 604 396 (6.5) 119 (3.2) 10 867/327 786 (3.3)
No charge 188/36 124 (0.5) 27 786/8 604 396 (0.3) 0 242/327 786 (0.1)
Other 1232/36 124 (3.4) 216 100/8 604 396 (2.5) 125 (3.3) 9312/327 786 (2.8)

Abbreviations: ED, emergency department; FNDs, functional neurological disorders; FSDs, functional somatic disorders (irritable bowel syndrome, fibromyalgia, chronic fatigue, etc); IQR, interquartile range; NA, not applicable; NEDS, Nationwide Emergency Department Sample.

a

Where applicable, data are presented with a weighted estimate sample (No.) and corresponding percentage of total (column %) or are otherwise described in parentheses based on nonmissing data. Unweighted value number is not shown; in cases in which the unweighted number is 10 or less, the weighted numbers are not available (denoted by ≤10). In some cases, the totals for each variable do not sum to the heading totals owing to missing data, which is explained in eTable 3 in the Supplement.

b

P values were calculated by t tests for continuous variables and by χ2 tests for categorical variables.

c

The totals of those who died in the hospital include those who died in the ED and those who were admitted and subsequently died.