Table 3. NIS 2008-2017 Data for Inpatient Charges in Adults 18 Years or Older Comparing FNDs With Other Neurological Disordersa.
| Year | Diagnosis | Sample characteristics | Total charges (95% CI), millions, $ | Mean (SEM) charge per patient, thousands, $ | |
|---|---|---|---|---|---|
| Sample size, No. with data (%) | Weighted sample, No. | ||||
| 2008 | FNDs | 3495 (98.5) | 16 396 | 407.2 (359.6-454.8) | 24.8 (0.9) |
| Other neurological disorders | 894 432 (98.0) | 4 211 739 | 161 330.7 (149 068.9-173 592.5) | 38.3 (1.0) | |
| MS | 28 530 (98.2) | 134 889 | 4748.1 (4321.5-5174.6) | 35.2 (1.0) | |
| Refractory epilepsy | 3356 (97.9) | 15 735 | 752.9 (548.9-957.0) | 47.9 (3.7) | |
| AHCD | 2927 (97.1) | 13 794 | 684.8 (601.2-768.3) | 49.6 (2.0) | |
| 2009 | FNDs | 3922 (99.0) | 18 903 | 497.6 (421.1-574.1) | 26.3 (1.0) |
| Other neurological disorders | 892 729 (98.7) | 4 363 285 | 183 276.7 (170 665.6-195 887.7) | 42.0 (1.0) | |
| MS | 28 337 (98.8) | 138 368 | 5304.9 (4850.5-5759.4) | 38.3 (1.0) | |
| Refractory epilepsy | 3432 (99.2) | 16 445 | 872.8 (510.7-1234.9) | 53.1 (4.3) | |
| AHCD | 2940 (98.8) | 14 387 | 790.2 (654.6-925.7) | 54.9 (3.4) | |
| 2010 | FNDs | 4185 (98.6) | 20 499 | 591.8 (518.4-665.3) | 28.9 (1.2) |
| Other neurological disorders | 921 508 (97.8) | 4 489 673 | 201 174.3 (187 295.0-215 053.5) | 44.8 (1.2) | |
| MS | 29 594 (98.4) | 143 599 | 5914.0 (5446.0-6382.0) | 41.2 (1.1) | |
| Refractory epilepsy | 4434 (98.3) | 21 700 | 1128.1 (836.8-1419.4) | 52.0 (3.3) | |
| AHCD | 2854 (97.8) | 13 934 | 879.9 (735.7-1024.1) | 63.1 (3.4) | |
| 2011 | FNDs | 4511 (98.6) | 20 943 | 636.6 (553.7-719.4) | 30.4 (1.2) |
| Other neurological disorders | 1 014 652 (97.8) | 4 747 239 | 219 745.8 (201 731.7-237 759.9) | 46.3 (1.3) | |
| MS | 32 330 (98.2) | 149 890 | 6353.7 (5803.0-6904.5) | 42.4 (1.2) | |
| Refractory epilepsy | 4487 (97.7) | 20 959 | 1276.5 (877.5-1675.5) | 60.9 (5.6) | |
| AHCD | 3160 (96.6) | 14 729 | 976.4 (775.4-1177.3) | 66.3 (5.3) | |
| 2012 | FNDs | 4404 (98.1) | 22 020 | 702.4 (652.9-751.9) | 31.9 (0.7) |
| Other neurological disorders | 929 961 (97.7) | 4 649 806 | 219 771.4 (212 498.7-227 044.1) | 47.3 (0.6) | |
| MS | 29 622 (97.9) | 148 110 | 6497.7 (6224.3-6771.0) | 43.9 (0.6) | |
| Refractory epilepsy | 4577 (97.8) | 22 885 | 1422.0 (1174.6-1669.4) | 62.1 (3.3) | |
| AHCD | 2947 (98.2) | 14 735 | 934.0 (843.7-1024.2) | 63.4 (2.4) | |
| 2013 | FNDs | 4331 (98.8) | 21 655 | 736.6 (678.9-794.2) | 34.0 (0.9) |
| Other neurological disorders | 920 119 (97.8) | 4 600 592 | 230 836.5 (223 077.8-238 595.2) | 50.2 (0.6) | |
| MS | 29 540 (98.0) | 147 700 | 6750.1 (6461.9-7038.4) | 45.7 (0.7) | |
| Refractory epilepsy | 4688 (97.7) | 23 440 | 1495.9 (1216.7-1775.1) | 63.8 (3.8) | |
| AHCD | 2839 (97.7) | 14 195 | 941.5 (848.6-1034.4) | 66.3 (2.7) | |
| 2014 | FNDs | 4689 (98.5) | 23 445 | 859.1 (794.3-923.9) | 36.6 (0.9) |
| Other neurological disorders | 927 215 (97.8) | 4 636 077 | 244 155.2 (235 823.5-252 486.8) | 52.7 (0.7) | |
| MS | 30 663 (98.1) | 153 315 | 7205.1 (6905.3-7504.9) | 47.0 (0.7) | |
| Refractory epilepsy | 5036 (98.2) | 25 180 | 1695.6 (1411.4-1979.8) | 67.3 (3.4) | |
| AHCD | 2880 (97.5) | 14 400 | 971.9 (888.5-1055.3) | 67.5 (2.2) | |
| 2015 (ICD-9-CM and ICD-10-CM) | Data not shown owing to transition in coding from ICD-9-CM to ICD-10-CM midyear | ||||
| 2016 (ICD-10-CM) | FNDs | 2980 (98.7) | 14 900 | 601.9 (552.0-651.8) | 40.4 (1.1) |
| Other neurological disorders | 941 837 (98.2) | 4 709 182 | 260 091.7 (251 204.8-268 978.5) | 55.2 (0.7) | |
| MS | 32 446 (98.4) | 162 230 | 8012.5 (7685.3-8339.6) | 49.4 (0.7) | |
| Refractory epilepsy | 5140 (98.0) | 25 700 | 1660.2 (1418.6-1901.8) | 64.6 (2.9) | |
| AHCD | 3073 (97.8) | 15 365 | 1055.1 (961.3-1149.0) | 68.7 (2.4) | |
| 2017 (ICD-10-CM) | FNDs | 4564 (99.7) | 22 820 | 1065.6 (970.9-1160.3) | 46.7 (1.6) |
| Other neurological disorders | 979 417 (99.5) | 4 897 084 | 302 041.3 (291 622.9-312 459.8) | 61.7 (0.8) | |
| MS | 33 869 (99.5) | 169 345 | 9323.9 (8930.7-9717.0) | 55.1 (0.8) | |
| Refractory epilepsy | 5936 (99.4) | 29 680 | 2044.8 (1765.9-2323.6) | 68.9 (2.7) | |
| AHCD | 3312 (99.6) | 16 560 | 1241.4 (1131.9-1350.9) | 75.0 (2.5) | |
Abbreviations: AHCD, anterior horn cell disease, including amyotrophic lateral sclerosis and spinal muscular atrophy; FNDs, functional neurological disorders; ICD-9-CM, International Classification of Diseases, Ninth Revision, Clinical Modification; ICD-10-CM, International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Clinical Modification; MS, demyelinating disease, including multiple sclerosis; NIS, National (Nationwide) Inpatient Sample.
a
All charge data are expressed in 2017 US dollars, and sample size is of nonmissing data with degree of missing data shown. Data from the NIS from 2008 to 2011 are adjusted using trend weights to account for change in database sampling.