Table 5. NEDS (2008-2017) Data for Charges in Adults and Pediatric Patients Comparing FNDs With Other Neurological Disordersa.
| Year | Diagnosis | Sample characteristics | Total charges (95% CI), millions, $ | Mean (SEM) charge per patient, thousands, $ | |
|---|---|---|---|---|---|
| Sample size, No. with data (%) | Weighted sample, No. | ||||
| NEDS ED charge data in adults aged ≥18 y comparing FNDs with other neurological disorders | |||||
| 2008 | FNDs | 3747 (75.9) | 16 358 | 42.1 (37.0-47.3) | 2.6 (0.1) |
| Other neurological disorders | 1 094 719 (76.9) | 4 732 422 | 10 989.1 (10 154.0-11 824.2) | 2.3 (0.1) | |
| MS | 37 298 (79.0) | 162 614 | 368.9 (336.2-401.6) | 2.3 (0.1) | |
| Refractory epilepsy | 1263 (66.6) | 5476 | 11.3 (9.2-13.4) | 2.1 (0.1) | |
| AHCD | 2515 (71.1) | 10 842 | 23.9 (21.4-26.5) | 2.2 (0.1) | |
| 2009 | FNDs | 4001 (79.1) | 18 024 | 54.8 (45.5-64.2) | 3.0 (0.2) |
| Other neurological disorders | 1 178 830 (79.4) | 5 244 173 | 14 350.3 (13 334.4-15 366.1) | 2.7 (0.1) | |
| MS | 39 011 (81.5) | 175 090 | 457.5 (417.2-497.8) | 2.6 (0.1) | |
| Refractory epilepsy | 1570 (75.6) | 7205 | 19.1 (14.6-23.5) | 2.6 (0.2) | |
| AHCD | 2846 (74.8) | 12 594 | 35.0 (30.0-39.9) | 2.8 (0.1) | |
| 2010 | FNDs | 4576 (79.9) | 20 599 | 66.2 (56.2-76.2) | 3.2 (0.2) |
| Other neurological disorders | 1 255 553 (81.1) | 5 601 910 | 16 291.9 (15 072.4-17 511.4) | 2.9 (0.1) | |
| MS | 42 309 (83.3) | 191 930 | 538.2 (490.7-585.7) | 2.8 (0.1) | |
| Refractory epilepsy | 1898 (72.9) | 8663 | 23.9 (20.0-27.8) | 2.8 (0.1) | |
| AHCD | 2973 (76.8) | 13 331 | 37.2 (32.6-41.9) | 2.8 (0.1 | |
| 2011 | FNDs | 4567 (81.6) | 20 955 | 74.9 (64.9-84.9) | 3.6 (0.2) |
| Other neurological disorders | 1 253 581 (80.5) | 5 769 999 | 18 008.8 (16 620.9-19 396.7) | 3.1 (0.1) | |
| MS | 45 002 (82.9) | 209 923 | 635.4 (582.0-688.8) | 3.0 (0.1) | |
| Refractory epilepsy | 2200 (78.5) | 10 193 | 31.2 (25.9-36.4) | 3.1 (0.1) | |
| AHCD | 2847 (76.5) | 13 257 | 39.1 (34.3-44.0) | 3.0 (0.1) | |
| 2012 | FNDs | 5352 (81.8) | 23 281 | 86.4 (74.8-98.1) | 3.7 (0.1) |
| Other neurological disorders | 1 347 245 (80.6) | 5 805 535 | 19 576.4 (18 038.3-21 114.4) | 3.4 (0.1) | |
| MS | 49 605 (84.1) | 216 612 | 702.1 (641.9-762.4) | 3.2 (0.1) | |
| Refractory epilepsy | 2481 (71.8) | 10 562 | 32.2 (26.7-37.7) | 3.1 (0.1) | |
| AHCD | 3093 (76.2) | 13 625 | 44.9 (38.6-51.1) | 3.3 (0.2) | |
| 2013 | FNDs | 5164 (81.6) | 23 646 | 93.8 (82.1-105.5) | 4.0 (0.1) |
| Other neurological disorders | 1 293 486 (79.6) | 5 954 324 | 22 234.2 (20 514.5-23 953.8) | 3.7 (0.1) | |
| MS | 48 927 (83.1) | 227 702 | 812.7 (742.3-883.1) | 3.6 (0.1) | |
| Refractory epilepsy | 2679 (73.9) | 12 823 | 40.7 (34.2-47.3) | 3.2 (0.2) | |
| AHCD | 3145 (75.8) | 14 515 | 50.0 (43.4-56.6) | 3.4 (0.1) | |
| 2014 | FNDs | 5706 (77.9) | 26 120 | 116.4 (101.6-131.3) | 4.5 (0.2) |
| Other neurological disorders | 1 363 887 (78.4) | 6 113 581 | 25 179.4 (23 073.0-27 285.9) | 4.1 (0.1) | |
| MS | 50 950 (82.2) | 228 764 | 882.6 (802.3-963.0) | 3.9 (0.1) | |
| Refractory epilepsy | 2869 (72.6) | 13 168 | 51.4 (43.1-59.7) | 3.9 (0.2) | |
| AHCD | 3383 (76.1) | 15 306 | 55.8 (48.5-63.1) | 3.6 (0.1) | |
| 2016 (ICD-10-CM) | FNDs | 3810 (80.5) | 16 983 | 73.3 (65.1-81.4) | 4.3 (0.2) |
| Other neurological disorders | 1 517 921 (82.1) | 6 779 450 | 30 529.3 (28 069.6-32 989.0) | 4.5 (0.1) | |
| MS | 56 791 (85.3) | 252 671 | 1077.9 (976.2-1179.5) | 4.3 (0.1) | |
| Refractory epilepsy | 4698 (81.4) | 20 453 | 89.4 (76.8-101.9) | 4.4 (0.2) | |
| AHCD | 3830 (80.5) | 16 855 | 72.1 (64.0-80.2) | 4.3 (0.1) | |
| 2017 (ICD-10-CM) | FNDs | 6834 (83.2) | 30 256 | 149.9 (134.6-165.2) | 5.0 (0.2) |
| Other neurological disorders | 1 644 240 (82.8) | 7 150 072 | 37 656.2 (34 644.3-40 668.1) | 5.3 (0.1) | |
| MS | 60 680 (84.9) | 264 815 | 1305.6 (1184.5-1426.8) | 4.9 (0.1) | |
| Refractory epilepsy | 5416 (81.9) | 23 669 | 113.9 (97.0-130.7) | 4.8 (0.2) | |
| AHCD | 3952 (79.1) | 17 294 | 81.7 (71.4-91.9) | 4.7 (0.2) | |
| NEDS ED charge data in pediatric patients aged 5-17 y comparing FND with other neurological disorders | |||||
| 2008 | FNDs | 405 (72.6) | 1844 | 3.7 (2.9-4.5) | 2.0 (0.1) |
| Other neurological disorders | 37 520 (77.2) | 165 875 | 317.3 (281.2-353.3) | 1.9 (0.1) | |
| MS | 196 (71.3) | 875 | 1.6 (1.0-2.1) | 1.8 (0.2) | |
| Refractory epilepsy | 243 (54.6) | 1105 | 1.8 (1.2-2.4) | 1.6 (0.1) | |
| AHCD | 108 (63.5) | 481 | 1.1 (0.6-1.6) | 2.3 (0.4) | |
| 2009 | FNDs | 370 (80.1) | 1656 | 3.6 (2.9-4.4) | 2.2 (0.2) |
| Other neurological disorders | 43 102 (79.7) | 192 060 | 418.8 (370.3-467.2) | 2.2 (0.1) | |
| MS | 146 (73.4) | 652 | 1.7 (1.0-2.3) | 2.6 (0.4) | |
| Refractory epilepsy | 300 (65.9) | 1314 | 3.0 (1.7-4.2) | 2.3 (0.3) | |
| AHCD | 110 (67.5) | 475 | 1.1 (0.7-1.5) | 2.3 (0.3) | |
| 2010 | FNDs | 482 (86.4) | 2154 | 5.4 (3.9-7.0) | 2.5 (0.3) |
| Other neurological disorders | 43 499 (83.5) | 195 015 | 441.1 (378.3-504.0) | 2.3 (0.1) | |
| MS | 174 (79.5) | 778 | 1.7 (1.1-2.4) | 2.2 (0.3) | |
| Refractory epilepsy | 439 (77.3) | 2007 | 4.3 (2.5-6.1) | 2.2 (0.2) | |
| AHCD | 117 (81.8) | 521 | 1.2 (0.7-1.7) | 2.2 (0.3) | |
| 2011 | FND | 542 (86.2) | 2569 | 7.0 (4.0-10.1) | 2.7 (0.2) |
| Other neurological disorders | 47 844 (85.1) | 227 620 | 515.8 (437.1-594.6) | 2.3 (0.1) | |
| MS | 207 (84.8) | 989 | 2.5 (1.6-3.4) | 2.5 (0.4) | |
| Refractory epilepsy | 546 (80.8) | 2643 | 6.1 (3.7-8.5) | 2.3 (0.3) | |
| AHCD | 118 (79.7) | 556 | 1.2 (0.6-1.9) | 2.2 (0.2) | |
| 2012 | FNDs | 604 (83.2) | 2678 | 7.4 (5.7-9.1) | 2.8 (0.2) |
| Other neurological disorders | 49 789 (81.4) | 218 941 | 525.7 (455.2-596.2) | 2.4 (0.1) | |
| MS | 199 (74.8) | 877 | 2.3 (1.5-3.0) | 2.6 (0.3) | |
| Refractory epilepsy | 585 (81.4) | 2441 | 7.0 (4.3-9.7) | 2.9 (0.3) | |
| AHCD | 112 (66.7) | 487 | 1.2 (0.6-1.8) | 2.5 (0.3) | |
| 2013 | FNDs | 489 (79.8) | 2333 | 6.3 (4.5-8.1) | 2.7 (0.2) |
| Other neurological disorders | 46 552 (79.2) | 219 074 | 563.5 (438.6-688.5) | 2.6 (0.1) | |
| MS | 202 (74.8) | 970 | 2.6 (1.5-3.8) | 2.7 (0.3) | |
| Refractory epilepsy | 626 (65.7) | 3125 | 9.2 (2.9-15.6) | 2.9 (0.6) | |
| AHCD | 113 (80.1) | 549 | 1.5 (0.9-2.1) | 2.8 (0.3) | |
| 2014 | FNDs | 566 (79.6) | 2659 | 9.1 (6.7-11.4) | 3.4 (0.2) |
| Other neurological disorders | 47 640 (79.7) | 217 986 | 573.0 (489.2-656.7) | 2.6 (0.1) | |
| MS | 214 (71.1) | 1007 | 2.9 (1.6-4.3) | 2.9 (0.5) | |
| Refractory epilepsy | 636 (64.7) | 3047 | 9.1 (6.1-12.1) | 3.0 (0.3) | |
| AHCD | 82 (69.5) | 390 | 1.0 (0.6-1.3) | 2.4 (0.2) | |
| 2016 (ICD-10-CM) | FNDs | 557 (88.0) | 2534 | 8.0 (5.8-10.2) | 3.1 (0.2) |
| Other neurological disorders | 67 369 (85.0) | 301 694 | 957.0 (787.6-1126.4) | 3.2 (0.1) | |
| MS | 325 (80.1) | 1427 | 5.3 (2.5-8.2) | 3.7 (0.6) | |
| Refractory epilepsy | 1708 (81.5) | 7683 | 26.1 (15.1-37.1) | 3.4 (0.3) | |
| AHCD | 186 (81.6) | 818 | 2.9 (1.6-4.1) | 3.5 (0.5) | |
| 2017 (ICD-10-CM) | FNDs | 728 (85.1) | 3262 | 12.9 (8.9-16.9) | 4.0 (0.4) |
| Other neurological disorders | 65 122 (85.7) | 283 755 | 959.4 (802.2-1116.6) | 3.4 (0.1) | |
| MS | 243 (70.6) | 1069 | 4.7 (2.7-6.7) | 4.4 (0.7) | |
| Refractory epilepsy | 1256 (75.7) | 5427 | 21.0 (13.8-28.1) | 3.9 (0.4) | |
| AHCD | 130 (73.5) | 583 | 2.5 (1.5-3.5) | 4.3 (0.7) | |
Abbreviations: AHCD, anterior horn cell disease, including amyotrophic lateral sclerosis and spinal muscular atrophy; ED, emergency department; FNDs, functional neurological disorders; ICD-9-CM, International Classification of Diseases, Ninth Revision, Clinical Modification; ICD-10-CM, International Statistical Classification of Diseases and Related Health Problems, Tenth Revision, Clinical Modification; MS, demyelinating disease, including multiple sclerosis; NEDS, Nationwide Emergency Department Sample.
a
All charge data are expressed in 2017 US dollars, and sample size is of nonmissing data with degree of missing data shown. Data are not shown for 2015 owing to transition in coding from ICD-9-CM to ICD-10-CM midyear.