Table 3.
CI values of CS with OA and ART in the A2780cisR cell line where drugs were added in equipotent ratios based on IC50 values.
| CI Values at | ||||||||
|---|---|---|---|---|---|---|---|---|
| Drug | Sequence (h) | Molar Ratio | ED50 | ED75 | ED90 | Dm | m | r |
| CS | N/A | N/A | N/A | 8.03 | 0.63 | 0.99 | ||
| OA | N/A | N/A | N/A | 56.44 | 0.40 | 1.00 | ||
| CS + OA | 0/0 | 1:4.05 | 0.57 | 0.49 | 0.50 | 2.88 | 0.61 | 1.00 |
| CS + OA | 0/4 | 0.63 | 0.42 | 0.32 | 3.15 | 0.72 | 1.00 | |
| CS + OA | 4/0 | 0.77 | 0.53 | 0.43 | 3.85 | 0.70 | 0.99 | |
| ART | N/A | N/A | N/A | 77.82 | 0.49 | 1.00 | ||
| CS + ART | 0/0 | 1:4.16 | 0.54 | 0.88 | 1.51 | 2.98 | 0.48 | 1.00 |
| CS + ART | 0/4 | 0.75 | 0.67 | 0.64 | 4.17 | 0.65 | 1.00 | |
| CS + ART | 4/0 | 0.87 | 0.80 | 0.78 | 4.82 | 0.64 | 1.00 | |
Dm: medium effect dose; m: exponent defining shape of the dose effect curve; r: reliability coefficient.