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. 2020 Oct 14;21(20):7597. doi: 10.3390/ijms21207597

Figure 2.

Figure 2

The TGF-β superfamily canonical and non-canonical pathways and their regulation for controlling the expression of targeted genes in osteoprogenitors and bone forming cells [120,133,159,216,217,218,219]. BAMBI: BMP and activin membrane-bound protein; FKBP12: FK506 binding protein of 12 kDa; LAP: latency associated peptide; LTBP: Latent TGF-β binding protein; PPM1A: protein phosphatase magnesium-dependent 1A; and SARA: Smad anchor for receptor activation protein. The figure was created using Servier Medical Art. https://smart.servier.com).