| AA3 | Anemoside A3 |
| AD | Alzheimer’s disease |
| AICD | APP intracellular domain |
| AMPA | α-amino-3-hydroxy-5-methyl-4isoxasolepropionic acid |
| ATP | Adenosine triphosphate |
| APP | Amyloid precursor protein |
| Aβ | Amyloid-β |
| BDNF | Brain-derived neurotrophic factor |
| BACE1 | β-site APP cleaving enzyme 1 |
| CA1 | cornu ammonis 1 |
| CAMKII | Calmodulin-dependent kinase II |
| Cdk-5 | Cyclin Dependent Kinase-5 |
| CK1/2 | Casein kinase 1/2 |
| CNS | Central nervous system |
| CREB | Cyclic adenosine monophosphate response element binding protein |
| CTEP | 2-chloro-4-[2-[2,5-dimethyl-1-[4-(trifluoromethoxy)phe-nyl]imidazol-4-yl]ethynyl] pyridine |
| DARPP-32 | Dopamine and cyclic adenosine monophosphate-regulated neuronal phosphoprotein |
| DCG-IV | (2S,2′R,3′R)-2-(2′,3′-dicarboxycyclopropyl)glycine |
| DHA | Dihydrokainic acid |
| DHPG | 3,5-dihydroxyphenylglycone |
| EAATs | Excitatory aminoacid transporters |
| EphB2 | Ephrin ligand receptor |
| ERK | Extracellular signal-related kinase |
| GABA | Gamma-Aminobutyric acid |
| GCPII | Glutamate caboxypeptidase II |
| GDNF | Glial cell line-derived neurotrophic factors |
| GPCRs | G protein-coupled receptors |
| GSK3β | Glycogen synthase kinase 3-β |
| HMW | High-molecular-weight |
| HNE | 4-Hydroxy-2-noneal |
| JNK | c-Jun N-terminal kinase |
| LTD | Long-term depression |
| LTP | Long-term potentiation |
| LMW | Low-molecular-weight |
| mTOR | mammalian Target of Rapamycin |
| MAP | Microtubule associated protein |
| MAPK | Mitogen-activated protein kinase |
| mPTP | mitochondrial permeability transition pore |
| MTEP | 3-((2-methyl-1,3-thiazol-4-yl)ethynyl)pyridine |
| NAA | N-acetylaspartate |
| NAAG | N-acetylaspartylglutamate |
| NAAGS-I | NAAG synthetase I |
| NAM | Negative allosteric modulator |
| NFTs | Neurofibrillary tangles |
| NMDA | N-methyl-D-aspartate |
| Non-PDPKs | Non-proline-directed protein kinases |
| PAG | Phosphate-activated glutaminase |
| PAM | Positive allosteric modulator |
| PSD95 | Postsynaptic density protein 95 |
| PDPKs | Proline-directed protein kinases |
| PI | Polyphosphoinositide |
| PKA | Protein kinase A |
| PrPc | Cellular prion protein |
| ROS | Reactive oxygen species |
| SAM | Silent allosteric modulator |
| sAPPα | Soluble APPα |
| sAPPβ | Soluble APPβ |
| STAT3 | Signal transducer and activator of transcription 3 |
| STEP61 | Striatal-enriched protein tyrosine phosphatase 61 |
| TARP | TCR Gamma Alternate Reading Frame Protein |
| TCA | Tricaboxylic acid |
| TGF-β1 | Transforming growth factor β1 |
| TMD | Transmembrane domain |
| TNF-α | Tumor necrosis factor-α |
| VGLUT1/2 | Vesicular glutamate transporters 1 and 2 |
| 2-PMPA | 2-(phosphonomethyl) pentanedioic acid |