Figure 2. Fetal partial pressure of oxygen in response to growth restriction and sildenafil treatment.

A, individual daily mean ± SD partial pressure of oxygen taken at individual time points ($P_{\mathrm{a}{\mathrm{O}}_2}$). B, total $P_{\mathrm{a}{\mathrm{O}}_2}$ mean during the first and second week of SC treatment. Groups are appropriately grown (AG, white, n = 6), saline‐treated fetal growth restricted (FGR, black, n = 7) and sildenafil‐treated fetal growth restricted (FGR_SC, grey, n = 7) fetuses. Duration of treatment is indicated by the SC administration bar. ^*Significant difference between FGR and AG; ^#significant difference between FGR_SC and AG. Daily physiological data collected over the duration of the experiment were analysed using a two‐way repeated measures ANOVA. Weekly mean physiological parameters were analysed using a one‐way ANOVA.