Table 1.
Description of the included patients
| Patient (Age, years; Sex) | CCI | Bleeding description | Admission ‐ Reversal (minutes) | Reversal ‐ Incision (minutes) | Surgery performed Post‐reversal | Blood Transfusion < 6 Hours Post‐Reversal | Hemostatic Effectiveness | In‐Hospital Mortality |
|---|---|---|---|---|---|---|---|---|
| 73F | 3 | Groin hematoma after percutaneous catheter ablation | 79 a | N/a | 2 Units | Poor | 0 | |
| 78M | 5 | Esophageal perforation | 106 | 61 | Right VATS, endoscopy upper GI, exploration neck | 0 | Excellent | 0 |
| 72M | 3 | GSW left abdomen, intra‐abdominal hemorrhage | 73 | −60 | Exploratory laparotomy, thoracotomy, distal pancreatectomy, splenectomy, repair of gastric injury, diaphragm repair, splenic flexure takedown | 46 Units | Poor | 1 |
| 53F | 1 | Subcapsular bleeding | 91 | 30 | Exploratory laparotomy, washout | 19 Units | Poor | 0 |
| 83M | 7 | Hematemesis, arterial extravasation in Whipple surgical bed (26 days prior) | 169 | >60 | Coil embolization of the proximal superior mesenteric artery branch. | 0 | Poor | 0 |
| 81M | 6 | Blunt traumatic hemopneumothorax, retroperitoneal hematoma | 66 | 61 | Exploratory laparotomy, right medial visceral rotation, abdominal packing, bilateral internal iliac artery embolization | 3 Units | Poor | 1 |
| 46M | 1 | Acute on chronic ascending aortic pseudoaneurysm | 343 | 814 | Reoperation ascending aortic pseudoaneurysm repair | 2 Units | Poor | 0 |
| 76M | 3 | Hemopericardium, mass effect in the right atrium and right ventricle with distention of inferior vena cava, retrosternal hematoma | 317 a | 81 | Mitral valve replacement, amputation left atrial appendage, isolation pulmonary vein, chest irrigation | 0 | Good | 0 |
| 63F | 4 | Intra‐abdominal hematoma (5" x 5"). | 404 | N/a | 0 | Excellent | 0 | |
| 73M | 11 | Splenic rupture | 59 | 300 | Exploratory laparotomy and splenectomy, second look laparotomy, third look laparotomy with bowel resection | 10 units | Poor | 1 |
| 85M | 6 | Blunt hemothorax | 202 | N/a | 2 units | Good | 0 | |
| 45F | 0 | Upper gastro‐intestinal bleeding | 378 | >30 | Upper GI endoscopy | 2 units | Good | 0 |
| 84M | 4 | Blunt traumatic prevertebral hematoma | 175 | 1080 | C4‐T1 Fusion | 0 | Good | 0 |
| 69F | 8 | Cervical epidural hematoma | 50 | N/a | 0 | Good | 1 | |
| 90F | 9 | Traumatic thigh hematoma | 131 | N/a | 2 Units | Good | 1 | |
| 96F | 10 | Ruptured type B aortic dissection, hemothorax | 63 | N/a | 0 | Poor | 1 | |
| 59M | 4 | Upper GI bleeding | 1 | >150 | Upper GI endoscopy | 2 Units | Poor | 0 |
| 78M | 6 | Cervical prevertebral hematoma, airway deviation | 103 | 1 | Emergent prevertebral hematoma evacuation | 0 | Excellent | 0 |
| 88M | 10 | Retroperitoneal bleed, gross hematuria, bladder perforation | 83 | N/a | 0 | Poor | 1 | |
| 95F | 11 | Type A aortic dissection into pericardium | 207 | N/a | 2 Units | Poor | 1 | |
| 50M | 5 | Upper GI bleeding | 41 | >60 | Upper GI endoscopy | 4 Units | Good | 0 |
Abbreivations: F, female sex; M, male sex; CCI, Charlson Comorbidity Index; GI, gastrointestinal; GSW, gunshot wound; N/a, not applicable; VATS, video‐assisted thoracoscopic surgery.
a
These patients were admitted to hospital prior to initiation of bleeding, the time listed indicates time between objective bleeding diagnosis to bolus infusion.