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. 2020 Oct 16;21(20):7679. doi: 10.3390/ijms21207679

Figure 6.

Figure 6

Schematic representation of Y-27632-induced neurite outgrowth in PC12 cells. Y-27632 causes Rac1 activation and leads to NOX1-mediated ROS generation. ROS then subsequently activate AKT and PAK1, which results in neurite outgrowth in PC12 cells.