Table 2.
Group, Sample | Induction Treatment | IS at Urine Collection | High CNI | Diagnosis |
---|---|---|---|---|
N1 | IL2RA | PR, CSA | − | NKF |
N2 | rATG | PR, TAC, MMF | − | NKF |
N3 | IL2RA | PR, TAC | − | NKF |
N4 | IL2RA | PR, TAC | − | NKF |
N5 | IL2RA | PR, TAC | − | NKF |
N6 | IL2RA | PR, TAC, MMF | − | NKF |
N7 | IL2RA | PR, TAC, MMF | − | NKF |
C8 | IL2RA | PR, TAC, MMF | + | aCNIT |
C9 | IL2RA | PR, TAC, MMF | + | aCNIT |
C10 | IL2RA | PR, CSA, MMF | + | cCNIT |
C11 | IL2RA | PR, TAC, MMF | + | aCNIT |
C12 | IL2RA | PR, TAC, MMF | + | aCNIT |
I13 | IL2RA | PR, TAC, MMF | − | IFTA (G2) |
I14 | IL2RA | PR, TAC, MMF | − | IFTA (G1) |
I15 | IL2RA | PR, TAC, MMF | − | IFTA (G2) |
I16 | IL2RA | PR, TAC, MMF | − | IFTA (G2) |
I17 | IL2RA | PR, CSA | − | IFTA (G2) |
IS, immunosuppressive treatment; CNI, calcineurin inhibitors; N, NKF, C, CNIT; I, IFTA; IL2RA, interleukin 2 receptor antagonists; rATG, rabbit anti-thymocyte globulin; PR, prednisone; CSA, cyclosporine A; TAC, tacrolimus; MMF, mycophenolate mofetil; NKF, normal kidney function; aCNIT, acute CNI toxicity; cCNIT, chronic CNI toxicity; IFTA (G), interstitial fibrosis and tubular atrophy (grade).