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. Author manuscript; available in PMC: 2020 Oct 27.
Published in final edited form as: Adv Protein Chem Struct Biol. 2019 Oct 21;118:273–288. doi: 10.1016/bs.apcsb.2019.09.005

Fig. 6. IDR in LOXL proteins.

Fig. 6

(A) Order/disorder probability prediction in the LOXL1 sequence. The zones where prediction confidence is > 95% is highlighted in red and the location for the enzymatic activity is indicated. (B) Comparison of order/disorder in LOXL family. (C) Comparison of order/disorder pattern in parent LOXL1 sequence and its mKATE2 chimera. (D) Examples of transgene LOXL1 constructs and their equivalent chimeras used to test aggregation propensity in overexpression assays.