Figure 2.

Immunologic parameters, neutrophilia and IL-6 in relation to clinical course at time of ICU admission, at day 4–7 (median 6 days)—when patients were still intubated—and prior to extubation if applicable (median 10 days). The median of 10 days differs from the median intubation time of 8.5 days (see main manuscript) since not all patients were intubated within 24 h post admission. Data from the unfavourable group (no extubation possible) were matched accordingly to achieve equivalent median days post ICU admission. Abbreviations: C-reactive-protein (CRP), Interleukin-(IL)-6, neutrophile/lymphocyte-ratio (NLR). This analysis includes 17 patients who had undergone intubation (1 patient each from the favourable and the unfavourable group were excluded, see methods section). Each datapoint represents one patient. Statistical significance for independent t-test between groups: n.s. = not significant, * = p < 0.05, ***p < 0.001. Statistical significance for repeated measure ANOVA † = not significant, § = p < 0.05, §§ = p < 0.01, §§§ = p < 0.001.