Table 1.

Characterization of resolvin subtypes and their receptors.

Omega-3	Resolvin Subtypes	Corresponding Receptors	Localisation	Function
EPA	RvE1	ChemR23 (ERV, CMKLR1)	Chemerin receptor 23 is expressed on NK cells, ILCs, macrophages, dendritic cells, and epithelial cells	stimulation of phagocytosis decrease in the level of proinflammatory cytokines
		BLT1
	RvE2	BLT1	Leukotriene LTB4 is expressed on human neutrophils, eosinophils, monocytes, macrophages, mast cells, dendritic cells, and T cells	reduction in neutrophil mobilization
DHA-	RvD1	ALX/FPR2	Expression on neutrophils, macrophages, monocytes, macrophages, and T cells	increase of phagocytosis prevention of the differentiation of T-lymphocytes towards Th1 and Th12, promotion of regulatory cell (Tr) formation
		DRV1/GPR32	The G-23 protein coupled receptor is expressed on human neutrophils, lymphocytes, macrophages, and monocytes, as well as vascular tissues
	RvD2	DRV1/GPR32		development of CD8a lymphocytes in the small intestine migration ability of immune cells recruitment of granulocytes decrease in blood pressure
		DRV2/GPR18	The G-18 protein coupled receptor is expressed on human and murine neutrophils, monocytes, and macrophages
	RvD3	DRV1/GPR32	The G-23 protein coupled receptor is expressed on human neutrophils, lymphocytes, macrophages, and monocytes, as well as vascular tissues	promotion of macrophage phagocytosis
	RvD4	G protein-coupled receptors: no data		inhibition of metastases and induced T cell responses
	RvD5	DRV1/GPR32	The G-23 protein coupled receptor is expressed on human neutrophils, lymphocytes, macrophages, and monocytes, as well as vascular tissues	expression of macrophages increase of phagocytosis.