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. 2020 Oct 21;17(20):7684. doi: 10.3390/ijerph17207684

Table 1.

Biological, medical and socio-demographic characteristics of the low-risk preterm and full-term late talkers and their parents and results of group comparisons.

Low-Risk Preterm
Late Talkers
(n = 26)
Full-Term
Late Talkers
(n = 35)
χ2/t df p
Children’s Characteristics
GA (weeks), Mean (SD) 33.90 (2.02) 39.37 (1.28) 12.95 59 <0.001
BW (grams), Mean (SD) 1991.58 (457.57) 3249.00 (530.02) 0.66 59 <0.001
Length of Stay in Hospital (days), Mean (SD) 21.61 (35.80) 2.63 (1.52) −2.70 59 0.003
Gender (Female), n (%) 8 (30.80) 12 (34.30) 0.08 1, 61 0.772
Firstborn, n (%) 14 (53.80) 16 (45.70) 2.69 1, 61 0.238
Twins, n (%) 15 (57.70) 0 (0) 26.78 1, 61 <0.001
Otitis Media, n (%) 1 (3.80) 2 (5.70) 0.11 1, 61 0.739
Family History of Language and/or Learning Disorders (LLD), n (%) 5 (19.20) 6 (17.10) 0.04 1, 61 0.834
Nursery School Attendance, n (%) 17 (65.40) 27 (77.10) 1.03 1, 61 0.311
Other Parent Input Besides Italian, n (%) 4 (15.40) 4 (11.40) 0.17 1, 60 0.683
Caesarean Section, n (%) 24 (92.30) 8 (22.90) 28.85 1, 61 <0.001
SGA, n (%) 5 (19.20) 1 (2.90) 4.51 1, 61 0.034
IVH I/II, n (%) 0 (0) 0 (0) - -
MV, n (%) 2 (7.70) 0 (0) 2.78 1, 61 0.095
RDS, n (%) 14 (53.80) 0 (0) 24.46 1, 61 <0.001
Apnea, n (%) 1 (3.80) 0 (0) 1.379 1, 61 0.242
BDP, n (%) 1 (3.80) 0 (0) 1.37 1, 61 0.242
Sepsis, n (%) 1 (3.80) 0 (0) 1.37 1, 61 0.242
ROP I/II, n (%) 0 (0) 0 (0) - -
Hyperbilirubinemia with Phototherapy, n (%) 17 (65.40) 3 (8.60) 21.85 1, 61 <0.001
Parents’ Characteristics
Mother’s Age (years), Mean (SD) 40.38 (5.26) 37.26 (5.33) −2.26 58 0.028
Father’s Age (years), Mean (SD) 42.63 (5.49) 39.41 (5.72) −2.07 51 0.043
Mothers with High
Educational Level (>13 years), n (%)
14 (53.80) 25 (71.40) 2.00 1, 61 0.157
Fathers with High
Educational Level (>13 years), n (%)
7 (26.90) 18 (51.40) 3.70 1, 61 0.054
Mother’s Nationality (Italian), n (%) 23 (88.50) 32 (91.40) 0.15 1, 61 0.700
Father’s Nationality (Italian), n (%) 23 (88.50) 32 (91.40) 0.15 1, 61 0.700

GA: gestational age; BW: birthweight; SGA: small for gestational age, infants with a birthweight < 10th percentile for gestational age; IVH I/II: intra-ventricular hemorrhage originating within the subependymal germinal matrix filling less than 10% (I grade) and 50% (II grade), respectively, of the ventricular area on parasagittal view; MV: mechanical ventilation; RDS: respiratory distress syndrome, acute illness coming on within 4–6 h of delivery, characterized clinically by respiratory rate ≥ 60/min, dyspnea and respiratory distress; Apnea: significant apnea was defined as more than four episodes of apnea/hour or more than two episodes of apnea/hour if ventilation with a bag and mask was required; BPD: bronchopulmonary dysplasia, needing both supplemental oxygen for ≥ 28 days and at 36 weeks of post-conception age; sepsis: presence of a positive blood culture and/or clinical and laboratory signs; ROP I/II: retinopathy of prematurity, vasoproliferative retinopathy resolved without a specific therapy before the presumed date of birth; Hyperbilirubinemia with phototherapy: hyperbilirubinemia needing phototherapy according to the criteria proposed by Gomella [45]. Missing data were present for the following variables: Other Parent Input Besides Italian, n = 1; Mother’s Age, n = 1; Father’s, n = 8. Significant results are highlighted in bold.