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. 2020 Oct 20;12(10):3055. doi: 10.3390/cancers12103055

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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MR lymphography using superparamagnetic iron oxide nanoparticles in a 77-year-old man with oral tongue cancer and a clinically negative neck. (A) T1-weigted 3D fast-field echo (FFE) show uptake of SPIO in two SLNs in level IIa (dotted arrow) & level IIb (arrow) left. (B) T2-weighted FFE shows clear negative contrast in corresponding SLNs, as a result of SPIO uptake. (C,D) Sagittal and coronal reconstruction of (A) shows the SLN in level IIa left (dotted arrow). (A–D) Informed consent has been obtained from this patient.