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. 2020 Oct 18;21(20):7700. doi: 10.3390/ijms21207700

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of PEA-m on levels of nerve growth factor (NGF). Immunohistochemical analysis showed no staining for NGF in the sham group (A). Increased NGF expression was observed in lumbar spinal cord collected 24 h after PO (B). A non-significant reduction was observed in PO + PEA-m post-treatment group (C), while low levels of this protein were found in rats treated with PEA-m both before and after plantar incision (D). The data are expressed as percentage of pixel cells (E). *** p < 0.001 vs. sham; ## p < 0.01 vs. PO.