Figure 5.
p65/NF-kB expression(fold of control) expression in MCF-7 (A), MDA-MB-231 (B) and AC-16 (C) cells, treated with ipilimumab mAb in the presence of hPBMCs under different condition (high glucose; low glucose; high glucose + empagliflozin at 500 nM; shifting from a high glucose to low glucose). Untreated or treated cells with an unrelated control IgG (control) were used as negative controls. Error bars depict means ± SD (n = 3). Statistical analysis was performed using paired t-test. *** p < 0.001. ** p < 0.01. * p < 0.05.